Darren studied at the University of Oxford where he received his Masters degree in 1993 and his DPhil in 1997 for work supervised by Prof Stephen G. Davies. After postdoctoral work with Professor Steven V. Ley CBE, FRS, he joined the faculty at the Department of Chemistry in Cambridge in 2000. In 2004 he took a Senior Lecturership at The University of Manchester and in 2007 he was promoted to Reader. In 2008 he moved to his current post at the University of Oxford where he is Professor of Chemistry and is the Knowles-Williams Tutorial Fellow in Organic Chemistry at Wadham College. His research program is centered on catalysis and synthetic organic chemistry and focuses on the development of new catalyst-enabled enantioselective synthetic methodologies and their application in synthesis.